Maine Biotechnology Services is pleased to be exhibiting at the 2012 BIO International Convention in Boston, MA.  MBS will be at Booth #1611, as part of the Biotechnology Association of Maine Booth. Both our Sales and Management teams will be attending BIO and available for meetings throughout the conference. 

Email Sales@mainebiotechnology.com to set up a meeting time today. 

MBS is offering a limited number of 1.0mg samples of MAB205P, Monoclonal Antibody to Chlamydia trachomatis LPS,  at a promotional price of $75.00 per mg.  Schedule shipment of your sample today.

Clone Determination               EVI-H                                            
Host                                             Mouse
Immunogen                                Chlamydia trachomatis LPS
Specificity                                  Chlamydia trachomatis LPS
Immunoglobulin Class             IgG2a κ
Purification                                Protein A chromatography                                                           
% Purity                                     > 95% pure by size-exclusion chromatography
pI                                                   > 8.0    
Buffer                                          0.15M PBS
Preservatives                              None                                                      
Applications                                IFA,IHC                                                                                               
Working dilution                       Determined by user
Storage                                        Store at -20C to -80C; avoid repeat freeze- thaw cycles                   

 Publications featuring MAB205P

A Predominant Antibody for Acquired Immunity to Chlamydial Genital Tract Reinfection

Characterization of Murine Monoclonal and Murine, Rabbit, and Human Polyclonal Antibodies against Chlamydial Lipopolysaccharide

Identification of Complex Proteins by Differential trachomatis Outer Membrane Identification of Chlamydia Proteomics

MBS is proud to have MAB206P, monoclonal antibody to polyethylene glycol (PEG), entered into a commercially available ELISA  kit for drug development.  Learn More about our PEG antibodies

Order Samples Today

Preliminary Technical Data 

In an effort to support our customers working with recombinant antigens, MBS developed a mouse monoclonal antibody against a polyhistidine (His) tag.  After meeting all the following development goals;  antibody with a high affinity, excellent functionality by Western Blot, and the ability to bind to both N and C terminal His-tags , MBS offers MAB230P.

Western Blot demonstrating the ability of MAB230P to bind recombinant
proteins containing  a 6XHis-tag at either the amino or carboxy terminus.

 
MAB230P, Monoclonal antibody to  polyhistidine (His) tag, has demonstrated an apparent affinity of 8.85 x 10^-12, able to detect His tagged antigen at picomolar concentrations (as determined by Forte Bio Octet Red)

Lanes are as follows:

1. MW Standard

2. N-term 6X-HIS TAG protein 100 ng/ml

3. N-term 6X-HIS TAG protein 25 ng/ml

4. N-term 6X-HIS TAG protein 5 ng/ml

5. MW Standard

6. C-term 6X-HIS TAG protein 100 ng/ml

7. C-term 6X-HIS TAG protein 25 ng/ml

8. C-term 6X-HIS TAG protein 5 ng/ml

 Indirect ELISA for the 4X-HIS:BSA conjugate

Yes, MBS has always offered anti-id Hybridoma development services.  In the past 2 years we have seen a significant increase in the number of requests as a result of the increase in antibody based therapies.  As novel humanized antibodies move through validation, the ability to identify the CDR regions (idiotype) of the drug antibody is critical.  MBS is proud to say that many of the antibodies developed for our pharmaceutical customers are currently being used in active clinical trials.   There is not a one size fits all solution or special protocol for making anti-idiotypic antibodies.  Instead, it’s the careful planning of experienced hybridoma development experts, tools to refine clone selection such as MultiPure and Octet Red, and communication with customers that has resulted in a very high level of success for anti-idiotypic projects.  Experience is the most important element in an anti-id project.  With approximately 1 in 4 of new hybridoma development projects having an anti-id goal, we are able to convey a high level of confidence to customers for these crucial, time sensitive projects. 

Contact us for a custom quote today.

Introducing MAB223P – MAB228P Monoclonal antibodies to human Norovirus GI and GII

 MBS is pleased to announce the release of two new monoclonal antibodies, MAB227P and MAB228P, to Norovirus complementing the current panel of Norovirus antibodies.  In addition to being broadly cross reactive to GII.4 genotypes, MAB227P has demonstrated the ability to work in surrogate neutralization assays.  MAB228P, developed against GI.1 1968 virus like particles (VLPs), has been shown to recognize additional GI genotypes. 

There are currently five known genogroups, of which three cause human disease:  GI, GII and GIV.  According to the CDC, since 2002 GII.4 has been the most common cause of Norovirus outbreaks.

                  * n/t – Not tested

Datasheets for all New Norovirus Antibodies

MAB223P Norovirus GII
MAB224P Norovirus GII
MAB225P Norovirus GII
MAB226P Norovirus GII
MAB227P Norovirus GII (Blocking)
MAB228P Norovirus GI

Contact us to reserve your sample today. 

New Control Antibodies to Human Ig Isotypes are available from MBS R&D. We are now offering: Fc, IgA, IgM, IgG1, IgG2, IgG3, IgG4, Kappa, and Lambda. Antibodies to murine isotypes, previously developed by MBS R&D are also available.  Contact us for sampling information.

The VPAC-1 receptor recently made news as a therapeutic target for patients undergoing cheomotherapy http://www.thrombogenics.com/html/pipeline6B.asp.  MBS has a Multipure plate of antibodies recognizing VPAC-1 available for sampling.  Contact us to order yours.