In Vitro Antibody Production
MBS offers in vitro cell culture production of monoclonal antibody in roller bottles. Our cGMP facility can accommodate 1L to 100L volumes per lot, generating milligram to gram quantities of antibody. Cell lines can be produced in our standard hybridoma media or in custom media formulations provided by the customer. Media formulations containing low IgG fetal bovine serum, serum-free media, or animal component-free media can be used for productions when more stringent requirements are necessary. Productions are designed to limit the introduction of endotoxin.
Monoclonal antibody produced in roller bottles is typically concentrated and purified prior to shipment.
In vitro Monoclonal Antibody Productions via Roller Bottle (3-4 weeks)
All incoming cell lines require MBS mycoplasma testing. Discuss mycoplasma decontamination services for lines that may be contaminated.
Cultures are grown in custom media and harvested for optimal antibody yield
Production volumes ranging from 1L to 100L
cGMP production report is provided
MBS also offers custom cell culture production of other mammalian cell lines (CHO, HEK 293) in addition to our standard hybridoma service offerings. Nunc cell factory productions are also available. Contact our Sales staff to discuss specific production requirements.
In vivo antibody productions in mouse ascites are also available for diagnostic uses or other customers seeking cost-effective large scale production quantities. Learn more about ascites production.
Discuss production requirements and further optimization with our sales staff at 207-797-5454 or [email protected]